SECURITIES AND EXCHANGE COMMISSION
                              Washington, DC 20549



                                    Form 8-K



                             Current Report Pursuant
                          to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934



        Date of Report (Date of Earliest Event Reported) January 26, 2004
                               ------------------

                          Mission West Properties, Inc.
                     --------------------------------------
             (Exact Name of Registrant as Specified in its Charter)


                                    Maryland
                                 ---------------
                 (State or Other Jurisdiction of Incorporation)


              1-8383                               95-2635431
            ----------                           --------------
     (Commission File Number)          (I.R.S. Employer Identification No.)


                10050 Bandley Drive, Cupertino, California 95014
             ------------------------------------------------------
                    (Address of Principal Executive Offices)


                                 (408) 725-0700
                               -------------------
              (Registrant's Telephone Number, Including Area Code)


          -------------------------------------------------------------
          (Former Name or Former Address, if Changed Since Last Report)


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ITEM 4.  CHANGES IN REGISTRANT'S CERTIFYING ACCOUNTANT.

     (a)(1) Previous independent accountants

          (i) On Janurary 26, 2004,  PricewaterhouseCoopers  LLP, San Francisco,
     California ("PWC"),  the independent  accountant  previously engaged as the
     principal  accountant  to audit the  financial  statements  of Mission West
     Properties, Inc., (the "Company"), resigned as independent auditors for the
     Company,  as stated in the letter  attached as Exhibit 16.1 of this report.
     PWC did not issue a report of  independent  auditors'  with  respect to the
     Company's 2003 financial statements prior to its resignation.

          (ii)  The  reports  of  PWC on the  Company's  consolidated  financial
     statements  for the past two fiscal years  contained no adverse  opinion or
     disclaimer of opinion and were not qualified or modified as to uncertainty,
     audit scope or accounting principles.

          (iii)  PWC  informed  the  Chairman  of  the  Audit  Committee  of the
     Company's  board of  directors  of PWC's  resignation  after  the  close of
     business on January 26, 2004, and subsequently met with the Audit Committee
     on January 30, 2004 to discuss the reasons for the resignation.

          (iv) In  connection  with its  audits for the two most  recent  fiscal
     years and through January 26, 2004, there have been no  disagreements  with
     PWC  on  any  matter  of  accounting  principles  or  practices,  financial
     statement disclosure,  or auditing scope or procedure,  which disagreements
     if not resolved to the  satisfaction  of PWC would have caused them to make
     reference  thereto in their  report on the  financial  statements  for such
     years.

          (v) During the two most recent  fiscal  years and through  January 26,
     2004, there have been no "reportable  events" (as defined in Regulation S-K
     Item   304(a)(1)(v))   other  than  an  event  of  the  type  described  in
     subparagraph (B) of such regulation as stated in the PWC letter attached as
     Exhibit 16.1 of this report.

     (2) The Company has not engaged new independent  accountants during the two
most recent fiscal years and any subsequent  interim  period.  The Company is in
discussions  to  engage a new  independent  accountant  to audit  the  Company's
financial statements for 2003.

     (3) The Company has asked PWC to furnish it with a letter  addressed to the
SEC stating whether it agrees or disagrees with the above  statements  within 10
business days from the date of this report.



ITEM 7.  FINANCIAL STATEMENTS AND EXHIBITS.

                                     - 2 -



     Exhibit 16.1 Letter of  Resignation  of  PricewaterhouseCoopers  LLP, dated
January 26, 2004.



                                   SIGNATURES

     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.


                                                 MISSION WEST PROPERTIES, INC.



Dated:  February 2, 2004                         By:  /s/ Carl E. Berg
                                                    ----------------------------
                                                    Carl E. Berg
                                                    Chief Executive Officer

                                     - 3 -


EXHIBIT 16.1 TO FORM 8-K

RE-TYPED FROM ORIGINAL LETTER


January 26, 2004

Mr. John C. Bolger
Audit Committee Chairman
Mission West Proeprties, Inc.
96 Southerland Drive
Atherton, CA 94027


Dear Mr. Bolger:

In accordance  with the terms of our  engangment  with Mission West  PRoperties,
Inc. (the  "Company") as described in our  engagement  letter dated November 10,
2003, PricewaterhouseCoopers may decline to issue an audit report as a result of
our  engagement  if,  for any reason  caused by or  relating  to the  affairs or
management of the Company,  we are unable to complete the audit.  The purpose of
this  letter is to inform you that the firm is unable to  complete  its audit of
the COmpany's  financial  statements for the year ended December 31, 2003 due to
such reasons and consequently we are resigning from this engagement.

We wish the Company all the best in the future.

/s/ PricewaterhouseCoopers LLP
PricewaterhouseCoopers LLP

cc: Carl E. Berg, Chairman of the Board and Chief Executive Officer

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