UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                  SCHEDULE 13D

                    UNDER THE SECURITIES EXCHANGE ACT OF 1934
                                 AMENDMENT NO. 3

                            Interpharm Holdings, Inc.
--------------------------------------------------------------------------------
                               (Name of Company)

                         Common Stock, $0.01 par value
--------------------------------------------------------------------------------
                        (Title of Class of Securities)

                                   460588106
--------------------------------------------------------------------------------
                      (CUSIP Number of Class of Securities)

           Joan P. Neuscheler                          Gloria M. Skigen
  Tullis-Dickerson Capital Focus III, L.P.        Martin, Lucas & Chioffi, LLP
  c/o Tullis-Dickerson Partners III, L.L.C.           177 Broad Street
       Two Greenwich Plaza, 4th Fl.                  Stamford, CT 06901
          Greenwich, CT 06830                          (203) 973-5222
            (203) 629-8700

--------------------------------------------------------------------------------

                  (Name, Address and Telephone Number of Person
                Authorized to Receive Notices and Communications)

                                 April 24, 2008

--------------------------------------------------------------------------------

                          (Date of Event which Requires
                            Filing of this Schedule)

If the filing person has previously filed a statement on Schedule 13G to report
the acquisition that is the subject of this Schedule 13D, and is filing this
schedule because of Sections 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check
the following box. [ ]

NOTE: Schedules filed in paper format shall include a signed original and five
copies of the schedule, including all exhibits. See ss.240.13d-7 for other
parties to whom copies are to be sent. * The remainder of this cover page shall
be filled out for a reporting person's initial filing on this form with respect
to the subject class of securities, and for any subsequent amendment containing
information which would alter disclosures provided in a prior cover page. The
information required on the remainder of this cover page shall not be deemed to
be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934
("ACT") or otherwise subject to the liabilities of that section of the Act but
shall be subject to all other provisions of the Act (however, SEE the NOTES).






                                 SCHEDULE 13D/A

--------------------------------------------------------------------------------
CUSIP NO.      460588106                               PAGE 2 OF 11 PAGES
--------------------------------------------------------------------------------

--------------------------------------------------------------------------------
    1     NAME OF REPORTING PERSON
          I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)

          Tullis-Dickerson Capital Focus III, L.P. IRS # 06-1621801
--------------------------------------------------------------------------------
    2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP         (a) [x]
                                                                   (b) [ ]

--------------------------------------------------------------------------------
    3     SEC USE ONLY

--------------------------------------------------------------------------------
    4     SOURCE OF FUNDS*

          WC
--------------------------------------------------------------------------------
    5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
          PURSUANT TO ITEMS 2(d) or 2(e)                               [ ]

--------------------------------------------------------------------------------
    6     CITIZENSHIP OR PLACE OF ORGANIZATION

          Delaware, United States of America
--------------------------------------------------------------------------------
                 7      SOLE VOTING POWER

                        0
                ----------------------------------------------------------------
NUMBER OF        8      SHARED VOTING POWER
SHARES
BENEFICIALLY            568,647 shares of Common Stock;
OWNED BY
EACH                    2,281,914 shares of Common Stock issuable upon exercise
REPORTING               of the Amended and Restated Warrants;
PERSON WITH
                        10,526,316 shares of Common Stock issuable upon
                        conversion of the Series D-1 Preferred Stock;

                        877,194 shares of Common Stock issuable upon
                        conversion of the Convertible Notes; and

                        307,017 shares of Common Stock issuable upon
                        conversion of the Note Warrants (1)
                ----------------------------------------------------------------
                 9      SOLE DISPOSITIVE POWER

                        0
                ----------------------------------------------------------------
                 10     SHARED DISPOSITIVE POWER

                        568,647 shares of Common Stock;

                        2,281,914 shares of Common Stock issuable upon exercise
                        of the Amended and Restated Warrants; and

                        10,526,316 shares of Common Stock issuable upon
                        conversion of the Series D-1 Preferred Stock;

                        877,194 shares of Common Stock issuable upon
                        conversion of the Convertible Notes; and

                        307,017 shares of Common Stock issuable upon
                        conversion of the Note Warrants (1)
------------------------------------------------------------------------------
    11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH PERSON

                        568,647 shares of Common Stock;

                        2,281,914 shares of Common Stock issuable upon exercise
                        of the Amended and Restated Warrants; and

                        10,526,316 shares of Common Stock issuable upon
                        conversion of the Series D-1 Preferred Stock;

                        877,194 shares of Common Stock issuable upon
                        conversion of the Convertible Notes; and

                        307,017 shares of Common Stock issuable upon
                        conversion of the Note Warrants (1))
--------------------------------------------------------------------------------
    12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
          CERTAIN SHARES*                                                [ ]
--------------------------------------------------------------------------------
    13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

          18% (see Item 5)(1)
--------------------------------------------------------------------------------
    14    TYPE OF REPORTING PERSON*

          PN
--------------------------------------------------------------------------------

-----------------------

(1) Does not include shares of Common Stock (including shares of Common Stock
and shares of Common Stock issuable upon the conversion of preferred stock and
exercise of warrants and options) held by parties to (i) the Irrevocable Proxy
Agreement other than the Reporting Persons, as discussed in Item 4 of the
Amendment No. 1 and (ii) the Proceeds Sharing Agreement, other than the
Reporting Persons, as discussed in Item 4 below.




                                 SCHEDULE 13D/A

--------------------------------------------------------------------------------
CUSIP NO.      460588106                               PAGE 3 OF 11 PAGES
--------------------------------------------------------------------------------

--------------------------------------------------------------------------------
    1     NAME OF REPORTING PERSON
          I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)

          Tullis-Dickerson Partners III, L.L.C. IRS # 06-1621800
--------------------------------------------------------------------------------
    2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP         (a) [x]
                                                                   (b) [ ]

--------------------------------------------------------------------------------
    3     SEC USE ONLY

--------------------------------------------------------------------------------
    4     SOURCE OF FUNDS*

          AF
--------------------------------------------------------------------------------
    5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
          PURSUANT TO ITEMS 2(d) or 2(e)                               [ ]

--------------------------------------------------------------------------------
    6     CITIZENSHIP OR PLACE OF ORGANIZATION

          Delaware, United States of America
--------------------------------------------------------------------------------
                 7      SOLE VOTING POWER

                        0
                ----------------------------------------------------------------
NUMBER OF        8      SHARED VOTING POWER
SHARES
BENEFICIALLY            568,647 shares of Common Stock;
OWNED BY
EACH                    2,281,914 shares of Common Stock issuable upon exercise
REPORTING               of the Amended and Restated Warrants;
PERSON WITH
                        10,526,316 shares of Common Stock issuable upon
                        conversion of the Series D-1 Preferred Stock;

                        877,194 shares of Common Stock issuable upon
                        conversion of the Convertible Notes; and

                        307,017 shares of Common Stock issuable upon
                        conversion of the Note Warrants (1)
                ----------------------------------------------------------------
                 9      SOLE DISPOSITIVE POWER

                        0
                ----------------------------------------------------------------
                 10     SHARED DISPOSITIVE POWER

                        568,647 shares of Common Stock;

                        2,281,914 shares of Common Stock issuable upon exercise
                        of the Amended and Restated Warrants; and

                        10,526,316 shares of Common Stock issuable upon
                        conversion of the Series D-1 Preferred Stock;

                        877,194 shares of Common Stock issuable upon
                        conversion of the Convertible Notes; and

                        307,017 shares of Common Stock issuable upon
                        conversion of the Note Warrants (1)
------------------------------------------------------------------------------
    11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH PERSON

                        568,647 shares of Common Stock;

                        2,281,914 shares of Common Stock issuable upon exercise
                        of the Amended and Restated Warrants; and

                        10,526,316 shares of Common Stock issuable upon
                        conversion of the Series D-1 Preferred Stock;

                        877,194 shares of Common Stock issuable upon
                        conversion of the Convertible Notes; and

                        307,017 shares of Common Stock issuable upon
                        conversion of the Note Warrants (1)
--------------------------------------------------------------------------------
    12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
          CERTAIN SHARES*                                                [ ]
--------------------------------------------------------------------------------
    13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

          18% (see Item 5)(1)
--------------------------------------------------------------------------------
    14    TYPE OF REPORTING PERSON*

          OO
--------------------------------------------------------------------------------

-----------------------

(1) Does not include shares of Common Stock (including shares of Common Stock
and shares of Common Stock issuable upon the conversion of preferred stock and
exercise of warrants and options) held by parties to (i) the Irrevocable Proxy
Agreement other than the Reporting Persons, as discussed in Item 4 of the
Amendment No. 1 and (ii) the Proceeds Sharing Agreement, other than the
Reporting Persons, as discussed in Item 4 below.




                                 SCHEDULE 13D/A

--------------------------------------------------------------------------------
CUSIP NO.      460588106                               PAGE 4 OF 11 PAGES
--------------------------------------------------------------------------------

--------------------------------------------------------------------------------
    1     NAME OF REPORTING PERSON
          I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS
          (ENTITIES ONLY)

          Joan P. Neuscheler
--------------------------------------------------------------------------------
    2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP         (a) [x]
                                                                   (b) [ ]

--------------------------------------------------------------------------------
    3     SEC USE ONLY

--------------------------------------------------------------------------------
    4     SOURCE OF FUNDS*

          AF
--------------------------------------------------------------------------------
    5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
          PURSUANT TO ITEMS 2(d) or 2(e)                               [ ]

--------------------------------------------------------------------------------
    6     CITIZENSHIP OR PLACE OF ORGANIZATION

          United States of America
--------------------------------------------------------------------------------
                 7      SOLE VOTING POWER

                        0
                ----------------------------------------------------------------
NUMBER OF        8      SHARED VOTING POWER
SHARES
BENEFICIALLY            568,647 shares of Common Stock;
OWNED BY
EACH                    2,281,914 shares of Common Stock issuable upon exercise
REPORTING               of the Amended and Restated Warrants;
PERSON WITH
                        10,526,316 shares of Common Stock issuable upon
                        conversion of the Series D-1 Preferred Stock;

                        877,194 shares of Common Stock issuable upon
                        conversion of the Convertible Notes; and

                        307,017 shares of Common Stock issuable upon
                        conversion of the Note Warrants (1)
                ----------------------------------------------------------------
                 9      SOLE DISPOSITIVE POWER

                        0
                ----------------------------------------------------------------
                 10     SHARED DISPOSITIVE POWER

                        568,647 shares of Common Stock;

                        2,281,914 shares of Common Stock issuable upon exercise
                        of the Amended and Restated Warrants; and

                        10,526,316 shares of Common Stock issuable upon
                        conversion of the Series D-1 Preferred Stock;

                        877,194 shares of Common Stock issuable upon
                        conversion of the Convertible Notes; and

                        307,017 shares of Common Stock issuable upon
                        conversion of the Note Warrants (1)
------------------------------------------------------------------------------
    11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH PERSON

                        568,647 shares of Common Stock;

                        2,281,914 shares of Common Stock issuable upon exercise
                        of the Amended and Restated Warrants; and

                        10,526,316 shares of Common Stock issuable upon
                        conversion of the Series D-1 Preferred Stock;

                        877,194 shares of Common Stock issuable upon
                        conversion of the Convertible Notes; and

                        307,017 shares of Common Stock issuable upon
                        conversion of the Note Warrants (1)
--------------------------------------------------------------------------------
    12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
          CERTAIN SHARES*                                                [ ]
--------------------------------------------------------------------------------
    13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

          18% (see Item 5)(1)
--------------------------------------------------------------------------------
    14    TYPE OF REPORTING PERSON*

          IN
--------------------------------------------------------------------------------

-----------------------

(1) Does not include shares of Common Stock (including shares of Common Stock
and shares of Common Stock issuable upon the conversion of preferred stock and
exercise of warrants and options) held by parties to (i) the Irrevocable Proxy
Agreement other than the Reporting Persons, as discussed in Item 4 of the
Amendment No. 1 and (ii) the Proceeds Sharing Agreement, other than the
Reporting Persons, as discussed in Item 4 below.




                                 SCHEDULE 13D/A

--------------------------------------------------------------------------------
CUSIP NO.      460588106                               PAGE 5 OF 11 PAGES
--------------------------------------------------------------------------------

--------------------------------------------------------------------------------
    1     NAME OF REPORTING PERSON
          I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)

          James L.L. Tullis
--------------------------------------------------------------------------------
    2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP         (a) [x]
                                                                   (b) [ ]

--------------------------------------------------------------------------------
    3     SEC USE ONLY

--------------------------------------------------------------------------------
    4     SOURCE OF FUNDS*

          AF
--------------------------------------------------------------------------------
    5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
          PURSUANT TO ITEMS 2(d) or 2(e)                               [ ]

--------------------------------------------------------------------------------
    6     CITIZENSHIP OR PLACE OF ORGANIZATION

          United States of America
--------------------------------------------------------------------------------
                 7      SOLE VOTING POWER

                        0
                ----------------------------------------------------------------
NUMBER OF        8      SHARED VOTING POWER
SHARES
BENEFICIALLY            568,647 shares of Common Stock;
OWNED BY
EACH                    2,281,914 shares of Common Stock issuable upon exercise
REPORTING               of the Amended and Restated Warrants;
PERSON WITH
                        10,526,316 shares of Common Stock issuable upon
                        conversion of the Series D-1 Preferred Stock;

                        877,194 shares of Common Stock issuable upon
                        conversion of the Convertible Notes; and

                        307,017 shares of Common Stock issuable upon
                        conversion of the Note Warrants (1)
                ----------------------------------------------------------------
                 9      SOLE DISPOSITIVE POWER

                        0
                ----------------------------------------------------------------
                 10     SHARED DISPOSITIVE POWER

                        568,647 shares of Common Stock;

                        2,281,914 shares of Common Stock issuable upon exercise
                        of the Amended and Restated Warrants; and

                        10,526,316 shares of Common Stock issuable upon
                        conversion of the Series D-1 Preferred Stock;

                        877,194 shares of Common Stock issuable upon
                        conversion of the Convertible Notes; and

                        307,017 shares of Common Stock issuable upon
                        conversion of the Note Warrants (1)
------------------------------------------------------------------------------
    11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH PERSON

                        568,647 shares of Common Stock;

                        2,281,914 shares of Common Stock issuable upon exercise
                        of the Amended and Restated Warrants; and

                        10,526,316 shares of Common Stock issuable upon
                        conversion of the Series D-1 Preferred Stock;

                        877,194 shares of Common Stock issuable upon
                        conversion of the Convertible Notes; and

                        307,017 shares of Common Stock issuable upon
                        conversion of the Note Warrants (1)
--------------------------------------------------------------------------------
    12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
          CERTAIN SHARES*                                                [ ]
--------------------------------------------------------------------------------
    13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

          18% (see Item 5)(1)
--------------------------------------------------------------------------------
    14    TYPE OF REPORTING PERSON*

          IN
--------------------------------------------------------------------------------

-----------------------

(1) Does not include shares of Common Stock (including shares of Common Stock
and shares of Common Stock issuable upon the conversion of preferred stock and
exercise of warrants and options) held by parties to (i) the Irrevocable Proxy
Agreement other than the Reporting Persons, as discussed in Item 4 of the
Amendment No. 1 and (ii) the Proceeds Sharing Agreement, other than the
Reporting Persons, as discussed in Item 4 below.




                                 SCHEDULE 13D/A

--------------------------------------------------------------------------------
CUSIP NO.      460588106                               PAGE 6 OF 11 PAGES
--------------------------------------------------------------------------------

--------------------------------------------------------------------------------
    1     NAME OF REPORTING PERSON
          I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)

          Thomas P. Dickerson
--------------------------------------------------------------------------------
    2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP         (a) [x]
                                                                   (b) [ ]

--------------------------------------------------------------------------------
    3     SEC USE ONLY

--------------------------------------------------------------------------------
    4     SOURCE OF FUNDS*

          AF
--------------------------------------------------------------------------------
    5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
          PURSUANT TO ITEMS 2(d) or 2(e)                               [ ]

--------------------------------------------------------------------------------
    6     CITIZENSHIP OR PLACE OF ORGANIZATION

          United States of America
--------------------------------------------------------------------------------
                 7      SOLE VOTING POWER

                        0
                ----------------------------------------------------------------
NUMBER OF        8      SHARED VOTING POWER
SHARES
BENEFICIALLY            568,647 shares of Common Stock;
OWNED BY
EACH                    2,281,914 shares of Common Stock issuable upon exercise
REPORTING               of the Amended and Restated Warrants;
PERSON WITH
                        10,526,316 shares of Common Stock issuable upon
                        conversion of the Series D-1 Preferred Stock;

                        877,194 shares of Common Stock issuable upon
                        conversion of the Convertible Notes; and

                        307,017 shares of Common Stock issuable upon
                        conversion of the Note Warrants (1)
                ----------------------------------------------------------------
                 9      SOLE DISPOSITIVE POWER

                        0
                ----------------------------------------------------------------
                 10     SHARED DISPOSITIVE POWER

                        568,647 shares of Common Stock;

                        2,281,914 shares of Common Stock issuable upon exercise
                        of the Amended and Restated Warrants; and

                        10,526,316 shares of Common Stock issuable upon
                        conversion of the Series D-1 Preferred Stock;

                        877,194 shares of Common Stock issuable upon
                        conversion of the Convertible Notes; and

                        307,017 shares of Common Stock issuable upon
                        conversion of the Note Warrants (1)
------------------------------------------------------------------------------
    11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH PERSON

                        568,647 shares of Common Stock;

                        2,281,914 shares of Common Stock issuable upon exercise
                        of the Amended and Restated Warrants; and

                        10,526,316 shares of Common Stock issuable upon
                        conversion of the Series D-1 Preferred Stock;

                        877,194 shares of Common Stock issuable upon
                        conversion of the Convertible Notes; and

                        307,017 shares of Common Stock issuable upon
                        conversion of the Note Warrants (1)
--------------------------------------------------------------------------------
    12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
          CERTAIN SHARES*                                                [ ]
--------------------------------------------------------------------------------
    13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

          18% (see Item 5)(1)
--------------------------------------------------------------------------------
    14    TYPE OF REPORTING PERSON*

          IN
--------------------------------------------------------------------------------

-----------------------

(1) Does not include shares of Common Stock (including shares of Common Stock
and shares of Common Stock issuable upon the conversion of preferred stock and
exercise of warrants and options) held by parties to (i) the Irrevocable Proxy
Agreement other than the Reporting Persons, as discussed in Item 4 of the
Amendment No. 1 and (ii) the Proceeds Sharing Agreement, other than the
Reporting Persons, as discussed in Item 4 below.




                                 SCHEDULE 13D/A

--------------------------------------------------------------------------------
CUSIP NO.      460588106                               PAGE 7 OF 11 PAGES
--------------------------------------------------------------------------------

--------------------------------------------------------------------------------
    1     NAME OF REPORTING PERSON
          I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)

          Lyle A. Hohnke
--------------------------------------------------------------------------------
    2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP         (a) [x]
                                                                   (b) [ ]

--------------------------------------------------------------------------------
    3     SEC USE ONLY

--------------------------------------------------------------------------------
    4     SOURCE OF FUNDS*

          AF
--------------------------------------------------------------------------------
    5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
          PURSUANT TO ITEMS 2(d) or 2(e)                               [ ]

--------------------------------------------------------------------------------
    6     CITIZENSHIP OR PLACE OF ORGANIZATION

          United States of America
--------------------------------------------------------------------------------
                 7      SOLE VOTING POWER

                        0
                ----------------------------------------------------------------
NUMBER OF        8      SHARED VOTING POWER
SHARES
BENEFICIALLY            568,647 shares of Common Stock;
OWNED BY
EACH                    2,281,914 shares of Common Stock issuable upon exercise
REPORTING               of the Amended and Restated Warrants;
PERSON WITH
                        10,526,316 shares of Common Stock issuable upon
                        conversion of the Series D-1 Preferred Stock;

                        877,194 shares of Common Stock issuable upon
                        conversion of the Convertible Notes; and

                        307,017 shares of Common Stock issuable upon
                        conversion of the Note Warrants (1)
                ----------------------------------------------------------------
                 9      SOLE DISPOSITIVE POWER

                        0
                ----------------------------------------------------------------
                 10     SHARED DISPOSITIVE POWER

                        568,647 shares of Common Stock;

                        2,281,914 shares of Common Stock issuable upon exercise
                        of the Amended and Restated Warrants; and

                        10,526,316 shares of Common Stock issuable upon
                        conversion of the Series D-1 Preferred Stock;

                        877,194 shares of Common Stock issuable upon
                        conversion of the Convertible Notes; and

                        307,017 shares of Common Stock issuable upon
                        conversion of the Note Warrants (1)
------------------------------------------------------------------------------
    11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH PERSON

                        568,647 shares of Common Stock;

                        2,281,914 shares of Common Stock issuable upon exercise
                        of the Amended and Restated Warrants; and

                        10,526,316 shares of Common Stock issuable upon
                        conversion of the Series D-1 Preferred Stock;

                        877,194 shares of Common Stock issuable upon
                        conversion of the Convertible Notes; and

                        307,017 shares of Common Stock issuable upon
                        conversion of the Note Warrants (1)
--------------------------------------------------------------------------------
    12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
          CERTAIN SHARES*                                                [ ]
--------------------------------------------------------------------------------
    13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

          18% (see Item 5)(1)
--------------------------------------------------------------------------------
    14    TYPE OF REPORTING PERSON*

          IN
--------------------------------------------------------------------------------

-----------------------

(1) Does not include shares of Common Stock (including shares of Common Stock
and shares of Common Stock issuable upon the conversion of preferred stock and
exercise of warrants and options) held by parties to (i) the Irrevocable Proxy
Agreement other than the Reporting Persons, as discussed in Item 4 of the
Amendment No. 1 and (ii) the Proceeds Sharing Agreement, other than the
Reporting Persons, as discussed in Item 4 below.




                                 SCHEDULE 13D/A

--------------------------------------------------------------------------------
CUSIP NO.      460588106                               PAGE 8 OF 11 PAGES
--------------------------------------------------------------------------------

--------------------------------------------------------------------------------
    1     NAME OF REPORTING PERSON
          I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)

          Timothy M. Buono
--------------------------------------------------------------------------------
    2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP         (a) [x]
                                                                   (b) [ ]

--------------------------------------------------------------------------------
    3     SEC USE ONLY

--------------------------------------------------------------------------------
    4     SOURCE OF FUNDS*

          AF
--------------------------------------------------------------------------------
    5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
          PURSUANT TO ITEMS 2(d) or 2(e)                               [ ]

--------------------------------------------------------------------------------
    6     CITIZENSHIP OR PLACE OF ORGANIZATION

          United States of America
--------------------------------------------------------------------------------
                 7      SOLE VOTING POWER

                        0
                ----------------------------------------------------------------
NUMBER OF        8      SHARED VOTING POWER
SHARES
BENEFICIALLY            568,647 shares of Common Stock;
OWNED BY
EACH                    2,281,914 shares of Common Stock issuable upon exercise
REPORTING               of the Amended and Restated Warrants;
PERSON WITH
                        10,526,316 shares of Common Stock issuable upon
                        conversion of the Series D-1 Preferred Stock;

                        877,194 shares of Common Stock issuable upon
                        conversion of the Convertible Notes; and

                        307,017 shares of Common Stock issuable upon
                        conversion of the Note Warrants (1)
                ----------------------------------------------------------------
                 9      SOLE DISPOSITIVE POWER

                        0
                ----------------------------------------------------------------
                 10     SHARED DISPOSITIVE POWER

                        568,647 shares of Common Stock;

                        2,281,914 shares of Common Stock issuable upon exercise
                        of the Amended and Restated Warrants; and

                        10,526,316 shares of Common Stock issuable upon
                        conversion of the Series D-1 Preferred Stock;

                        877,194 shares of Common Stock issuable upon
                        conversion of the Convertible Notes; and

                        307,017 shares of Common Stock issuable upon
                        conversion of the Note Warrants (1)
------------------------------------------------------------------------------
    11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH PERSON

                        568,647 shares of Common Stock;

                        2,281,914 shares of Common Stock issuable upon exercise
                        of the Amended and Restated Warrants; and

                        10,526,316 shares of Common Stock issuable upon
                        conversion of the Series D-1 Preferred Stock;

                        877,194 shares of Common Stock issuable upon
                        conversion of the Convertible Notes; and

                        307,017 shares of Common Stock issuable upon
                        conversion of the Note Warrants (1)
--------------------------------------------------------------------------------
    12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
          CERTAIN SHARES*                                                [ ]
--------------------------------------------------------------------------------
    13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

          18% (see Item 5)(1)
--------------------------------------------------------------------------------
    14    TYPE OF REPORTING PERSON*

          IN
--------------------------------------------------------------------------------

-----------------------

(1) Does not include shares of Common Stock (including shares of Common Stock
and shares of Common Stock issuable upon the conversion of preferred stock and
exercise of warrants and options) held by parties to (i) the Irrevocable Proxy
Agreement other than the Reporting Persons, as discussed in Item 4 of the
Amendment No. 1 and (ii) the Proceeds Sharing Agreement, other than the
Reporting Persons, as discussed in Item 4 below.







                                 SCHEDULE 13D/A

The Schedule 13D filed on June 6, 2006 (the "Schedule 13D") by  Tullis-Dickerson
Capital Focus III, L.P.  ("Capital Focus III"),  Tullis-Dickerson  Partners III,
L.L.C. ("Partners III"), Joan P. Neuscheler  ("Neuscheler"),  James L. L. Tullis
("Tullis"),  Thomas P. Dickerson  ("Dickerson"),  Lyle A. Hohnke  ("Hohnke") and
Timothy M. Buono  ("Buono" and together  with Capital  Focus III,  Partners III,
Neuscheler,  Tullis,  Dickerson and Hohnke, the "Reporting Persons") relating to
the common stock, par value $0.01 per share (the "Common Stock"),  of Interpharm
Holdings, Inc. (the "Issuer"), as amended by Amendment No. 1 to the Schedule 13D
filed on November 16, 2007 (the  "Amendment  No. 1") and  Amendment No. 2 to the
Schedule  13D filed on  February  29,  2008 (the  "Amendment  No. 2"), is hereby
amended as set forth in this Amendment No. 3.

ITEM 4. PURPOSE OF TRANSACTION.

ITEM 4 OF THE SCHEDULE 13D IS HEREBY AMENDED TO ADD THE FOLLOWING:

On April  24,  2008 the  Issuer,  Amneal  Pharmaceuticals  of New York,  LLC,  a
Delaware limited liability company,  ("Amneal") and certain  shareholders of the
Issuer,  including,  but not  limited  to,  Capital  Focus III,  (the  "Majority
Shareholders"),  with  respect to only  certain  provisions  specified  therein,
entered  into  that  certain  Asset  Purchase  Agreement  (the  "Asset  Purchase
Agreement"),  pursuant to which the Issuer agreed to sell  substantially  all of
its assets to Amneal and Amneal agreed to assume certain  specified  liabilities
of the Issuer (the "Asset Purchase").

Pursuant to the Asset  Purchase  Agreement,  the Majority  Shareholders  agreed,
among other things,  (i) to cease any activities or discussions with any parties
that may be on going with respect to any Acquisition Proposal (as defined in the
Asset Purchase  Agreement),  not to solicit or initiate any Acquisition Proposal
and  not to  participate  in  any  discussions  or  negotiations  regarding  any
Acquisition Proposal, subject to certain exceptions, and (ii) not to withdraw or
modify  its  Transaction  Written  Consent  (as  defined  in the Asset  Purchase
Agreement).

On April 24, 2008, Capital Focus III, Aisling Capital II, L.P.  ("Aisling",  and
Aisling  together  with  Capital  Focus III,  the "Series D-1  Holders"),  Ravis
Holdings I, LLC ("Ravis  Holdings"),  P&K Holdings,  LLC ("P&K  Holdings"),  Dr.
Maganlal K. Sutaria,  Perry Sutaria,  Raj Holdings I, LLC ("Raj  Holdings",  and
together  with Perry  Sutaria,  and Dr.  Maganlal  K.  Sutaria,  the "Series A-1
Holders",  and the Series A-1 Holders together with the Series D-1 Holders,  the
"Preferred  Holders"),  Raj Sutaria,  Ravi Sutaria and  Bhupatalal  K.  Sutaria,
entered into that certain  Proceeds  Sharing  Agreement (the  "Proceeds  Sharing
Agreement")  pursuant to which the parties  agreed to vote in favor of the Asset
Purchase.

Pursuant to the  Proceeds  Sharing  Agreement,  the Series D-1  Holders  agreed,
severally  and not  jointly,  that,  if, as a result of the Asset  Purchase,  it
receives  distributions  from the Issuer based on its holdings of the Series D-1
Preferred  Stock (as defined in the  Amendment  No. 1) in excess of  $7,000,000,
such  Series D-1 Holder may  direct  the Issuer to  distribute  or shall  itself
distribute,  such excess amount to all holders of the Common Stock of the Issuer
on a pro rata basis;  provided,  that, the amount  distributed to the holders of
Common Stock by the Series D-1 Holders shall not exceed $3,000,000.  Pursuant to
the Proceeds Sharing Agreement,  the Preferred Holders agreed, severally and not
jointly,  that,  if, as a result of the Asset  Purchase,  the Series D-1 Holders
receive  distributions from the Issuer based on their holdings of the Series D-1
Preferred  Stock in excess of $2,000,000,  each Preferred  Holder may direct the
Issuer to distribute or shall itself distribute,  the amounts set forth opposite
such Preferred  Holder's name in Schedule A of the Proceeds Sharing Agreement to
Bhupatalal K. Sutaria.

By virtue of the Proceeds Sharing Agreement, the Reporting Persons may be deemed
to have  formed a  "group,"  within  the  meaning  of  Section  13(d)(3)  of the
Securities  Act of 1934,  with the parties to the  Proceeds  Sharing  Agreement.
However,  each of the Reporting Persons  expressly  disaffirm the existence of a
group with the parties to the Proceeds Sharing Agreement and expressly disclaims
beneficial  ownership  of the shares of Common Stock  beneficially  owned by the
other parties to the Proceeds Sharing Agreement.




Upon  information and belief,  the other parties to Proceeds  Sharing  Agreement
will be filing their own Schedule 13D separately, with respect to the Issuer.

The  foregoing  description  of the Asset  Purchase  Agreement  and the Proceeds
Sharing  Agreement  is a  summary  only  and is  qualified  in its  entirety  by
reference to the Asset  Purchase  Agreement and the Proceeds  Sharing  Agreement
which are filed as Exhibits  14 and 15 hereto,  respectively,  and  incorporated
herein by reference.

ITEM 5. INTEREST IN SECURITIES OF THE COMPANY.

ITEM 5 OF THE SCHEDULE 13D IS HEREBY AMENDED AND RESTATED AS FOLLOWS:

(a) As of the date of this Amendment No. 3, the Reporting  Persons may be deemed
to  beneficially  own 14,561,088  shares of Common Stock including (i) 2,281,914
shares of Common  Stock  issuable  to  Capital  Focus III upon  exercise  of the
Amended  and  Restated  Warrants  (as  defined in the  Amendment  No.  1);  (ii)
10,526,316  shares of Common Stock issuable to Capital Focus III upon conversion
of the Series D-1  Preferred  Stock (as defined in the  Amendment  No. 1); (iii)
877,194 shares of Common Stock issuable to Capital Focus III upon  conversion of
the  Convertible  Notes (as defined in the Amendment No. 1); (iv) 307,017 shares
of Common  Stock  issuable  to  Capital  Focus III upon  conversion  of the Note
Warrants (as defined in the Amendment  No. 1); and (v) 568,647  shares of Common
Stock  currently  owned by Capital  Focus III. The  14,561,088  shares of Common
Stock that the Reporting Persons may be deemed to beneficially own represent 18%
of the Common Stock. The percentages used in this Amendment No. 3 are calculated
based upon  66,738,422  shares of Common  Stock  outstanding  as of February 11,
2008,  which is the total number shares of Common Stock  outstanding  as of such
date as reported by the Issuer in its  Quarterly  Report on Form 10-Q filed with
the SEC on  February  15,  2008.  Partners  III is the sole  general  partner of
Capital Focus III. Neuscheler,  Tullis, Dickerson, Hohnke and Buono share voting
and/or  dispositive  power over all shares of Common Stock held by Capital Focus
III. The Reporting Persons disclaim beneficial ownership of the shares of Common
Stock  beneficially  owned  except to the  extent of their  pecuniary  interests
therein. As discussed in Item 4 of Amendment No. 1, the Reporting Persons may be
deemed to be a group with the parties to the  Irrevocable  Proxy  Agreement  (as
defined in the  Amendment  No. 1) within the meaning of Section  13(d)(3) of the
Securities and Exchange Act of 1934, however, the Reporting Persons disclaim the
creation  of a group with the parties to the  Irrevocable  Proxy  Agreement.  As
discussed  in Item 4 above,  the  Reporting  Persons may be deemed to be a group
with the parties to the Proceeds Sharing Agreement within the meaning of Section
13(d)(3) of the  Securities  and Exchange Act of 1934,  however,  the  Reporting
Persons  disclaim  the  creation  of a group with the  parties  to the  Proceeds
Sharing Agreement.

(b) Partners III is the sole general  partner of Capital Focus III.  Neuscheler,
Tullis,  Dickerson,  Hohnke and Buono share voting and/or dispositive power over
all shares.  These individuals  disclaim  beneficial  ownership of the shares of
Common Stock  beneficially  owned by the above entities  except to the extent of
their pecuniary interests therein.  The Reporting Persons disclaim their ability
to direct the voting of Issuer  shares,  other than those held  directly  by the
Reporting  Persons,  as a  result  of the  Irrevocable  Proxy  Agreement  or the
Proceeds  Sharing  Agreement  as  discussed  in Item 4 of  Amendment  No. 1. The
Reporting  Persons disclaim their ability to direct the voting of Issuer shares,
other than those held  directly  by the  Reporting  Persons,  as a result of the
Proceeds Sharing Agreement as discussed in Item 4 above.

(c) During the last sixty days there were no  transactions  in the Common  Stock
effected.  The Reporting  Persons disclaim their ability to direct the voting of
the Common Stock as a result of the Irrevocable  Proxy Agreement as discussed in
Item 4 of Amendment  No. 1. The  Reporting  Persons  disclaim  their  ability to
direct  the  voting  of the  Common  Stock as a result of the  Proceeds  Sharing
Agreement as discussed in Item 4 above.

(d) The partners or members of Capital Focus III and Partners III have the right
to participate indirectly in the receipt of dividends from, or proceeds from the
sale of,  the  shares  of  Common  Stock in  accordance  with  their  respective
ownership interests in their respective entities.
                                       2




(e) Not applicable.

ITEM 6. CONTRACTS, ARRANGEMENTS, UNDERSTANDINGS OR RELATIONSHIPS WITH RESPECT
TO SECURITIES OF THE ISSUER.

As described  in Item 4 above,  on April 24, 2008,  Interpharm  Holdings,  Inc.,
Amneal  Pharmaceuticals of New York, LLC and certain  shareholders of Interpharm
Holdings,  Inc. listed on the signature  pages attached  thereto entered into an
Asset Purchase Agreement, a copy of which is attached as Exhibit 14 hereto.

As described in Item 4 above, on April 24, 2008,  Tullis-Dickerson Capital Focus
III, L.P., Aisling Capital II, LP, Ravis Holdings I, LLC, P&K Holdings, LLC, Dr.
Maganlal K.  Sutaria,  Perry  Sutaria,  Raj Holdings I, LLC,  Raj Sutaria,  Ravi
Sutaria and Bhupatalal K. Sutaria,  entered into a Proceeds Sharing Agreement, a
copy of which is attached as Exhibit 15 hereto.

ITEM 7. MATERIAL TO BE FILED AS EXHIBITS.

ITEM 7 OF THE SCHEDULE 13D IS HEREBY AMENDED TO ADD OF THE FOLLOWING:

14. Asset  Purchase  Agreement,  dated April 24, 2008,  by and among  Interpharm
Holdings, Inc., Amneal Pharmaceuticals of New York, LLC and certain shareholders
of Interpharm  Holdings,  Inc.  listed on the signature  pages attached thereto.

15.   Proceeds   Sharing   Agreement,   dated  April  24,  2008,  by  and  among
Tullis-Dickerson Capital Focus III, L.P., Aisling Capital II, LP, Ravis Holdings
I, LLC, P&K Holdings,  LLC, Dr. Maganlal K. Sutaria, Perry Sutaria, Raj Holdings
I, LLC, Raj Sutaria, Ravi Sutaria and Bhupatalal K. Sutaria.


                                       3



                                   SIGNATURES

     After reasonable inquiry and to the best of his knowledge and belief,  each
of the undersigned certifies that the information set forth in this statement is
true, complete and correct.


April 28, 2008                  TULLIS-DICKERSON CAPITAL FOCUS III, L.P.

                                BY:      TULLIS-DICKERSON PARTNERS III, L.L.C.,
                                ITS:     GENERAL PARTNER

                                By:      /s/ Joan P. Neuscheler
                                         ---------------------------------------
                                         ---------------------------------------
                                         JOAN P. NEUSCHELER
                                         Principal

April 28, 2008                           TULLIS-DICKERSON PARTNERS III, L.L.C.

                                By:      /s/ Joan P. Neuscheler
                                         ---------------------------------------
                                         ---------------------------------------
                                         JOAN P. NEUSCHELER
                                         Principal


April 28, 2008                           /s/ Joan P. Neuscheler
                                         ---------------------------------------
                                         ---------------------------------------
                                         JOAN P. NEUSCHELER

April 28, 2008                           /s/ James L.L. Tullis

                                         ---------------------------------------
                                         JAMES L.L. TULLIS

April 28, 2008                          /s/ Thomas P. Dickerson
                                         ---------------------------------------
                                         ---------------------------------------
                                         THOMAS P. DICKERSON

April 28, 2008                           /s/ Lyle A. Hohnke
                                         ---------------------------------------
                                         ---------------------------------------
                                         LYLE A. HOHNKE

April 28, 2008                           /s/ Timothy M. Buono
                                         ---------------------------------------
                                         ---------------------------------------
                                         TIMOTHY M. BUONO






                                  EXHIBIT INDEX

The Exhibit Index of the Schedule 13D is hereby amended to add the following:

14. Asset  Purchase  Agreement,  dated April 24, 2008,  by and among  Interpharm
Holdings, Inc., Amneal Pharmaceuticals of New York, LLC and certain shareholders
of Interpharm Holdings, Inc. listed on the signature pages attached thereto.

15.   Proceeds   Sharing   Agreement,   dated  April  24,  2008,  by  and  among
Tullis-Dickerson Capital Focus III, L.P., Aisling Capital II, LP, Ravis Holdings
I, LLC, P&K Holdings,  LLC, Dr. Maganlal K. Sutaria, Perry Sutaria, Raj Holdings
I, LLC, Raj Sutaria, Ravi Sutaria and Bhupatalal K. Sutaria.